The establishment of self-disinfecting surfaces is an important method to avoid surface contamination.Recently, paints with antimicrobial properties have been developed to be applied on different surfaces, avoiding contamination with pathogens.In this work, self-disinfecting paints containing Chloroxylenol (CLX), Terpineol (TRP), and a mixture of b
DiiS: A Biomedical Data Access Framework for Aiding Data Driven Research Supporting FAIR Principles
Vast amounts of clinical and biomedical research data are produced daily.These data can help enable data driven healthcare through novel biomedical discoveries, improved diagnostics processes, epidemiology, and education.However, finding, and gaining access to these data and relevant metadata that are necessary to achieve these goals remains a chal
Abnormal repression of SHP-1, SHP-2 and SOCS-1 transcription sustains the activation of the JAK/STAT3 pathway and the progression of the disease in multiple myeloma.
Sustained activation of JAK/STAT3 signaling pathway is classically described in Multiple Myeloma (MM).One explanation could be the silencing of the JAK/STAT suppressor genes, through the hypermethylation of SHP-1 and SOCS-1, previously demonstrated in MM cell lines or in whole bone marrow aspirates.The link between such suppressor gene silencing an
Impact of Tailored Interventions to Reduce Drug Use and Sexual Risk Behaviors Among Homeless Gay and Bisexual Men
A randomized controlled trial was conducted with homeless gay and bisexual men to assess the impact of two culturally sensitive intervention programs on reduction of drug use and risky sexual behavior.In this study, gay and bisexual men between 18 and 46 years of age were randomly assigned to one of two culturally sensitive behavioral intervention
Immuno-Electron and Confocal Laser Scanning Microscopy of the Glycocalyx
The glycocalyx (GCX), CHLOROPHYLL LIQUIDE a pericellular carbohydrate rich hydrogel, forms a selective barrier that shields the cellular membrane, provides mechanical support, and regulates the transport and diffusion of molecules.The GCX is a fragile structure, making it difficult to study by transmission electron microscopy (TEM) and confocal las